Endocrine Abstracts

Context: In men, a decline of mean circulating testosterone level is seen with increasing age. This decline is associated with an increase in the mean levels of LH and FSH, albeit insufficient to maintain testosterone at its original level. It has been speculated that a higher sensitivity of the hypothalamus and/or pituitary for the feedback effect of circulating testosterone in older men is responsible.Objective: To compare the effect of experimentally ...